Tay-Sachs Disease
Progressive neurological disorder affecting nerve cells, causing severe developmental regression and typically fatal by age 5. Most common in Ashkenazi Jewish populations.
Learn More →1 in 4
Ashkenazi Jews carry at least one genetic mutation
100+
Known Jewish genetic conditions
90%
Reduction in Tay-Sachs cases through screening
1 in 40
Ashkenazi Jews have BRCA mutations
Most Common Genetic Conditions
Gaucher Disease
Most common genetic disease affecting Ashkenazi Jews. Enzyme deficiency causing organ enlargement and bone problems. Type 1 is manageable with treatment.
Learn More →BRCA Gene Mutations
Hereditary breast and ovarian cancer predisposition. Significantly higher rates in Ashkenazi Jewish women, with specific founder mutations.
Learn More →Cystic Fibrosis
Affects lungs and digestive system with thick mucus production. Higher carrier rates in Ashkenazi Jewish populations compared to general population.
Learn More →Familial Dysautonomia
Affects autonomic nervous system controlling vital functions. Almost exclusively found in Ashkenazi Jewish population.
Learn More →Canavan Disease
Progressive brain disorder affecting white matter development. Causes severe developmental delays and shortened lifespan.
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Medical Disclaimer: This website provides educational information only and should not replace professional medical advice, diagnosis, or treatment. Always consult with qualified healthcare providers regarding genetic testing and medical decisions.
Resources & Support
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